Northeast Missouri Vacation Packages

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Your Northeast Missouri Vacation

When you're ready for your next big adventure, our Northeast Missouri vacation packages are the answer. Dining and culture are among the many things that make this destination truly unforgettable. Kick off your trip to Northeast Missouri with some time exploring St. Louis visiting popular sights like Enterprise Centre and Busch Stadium. St. Charles is another top city that draws travellers from far and wide. Ameristar Casino St. Charles and Westport Plaza are two of the leading places to see in this destination. From the moment you book your Northeast Missouri vacation to when you get back home, Expedia will take care of you each step of the way.

Top Northeast Missouri Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown

3 out of 5
Midtown
Price was CA $1,628, price is now CA $1,366 per person
CA $1,366
per person
Dec 16 - Dec 23
found 17 hours ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
7.8/10 Good! (1,001 reviews)

The Wildwood Hotel

The Wildwood Hotel

3.5 out of 5
Price was CA $2,200, price is now CA $1,395 per person
CA $1,395
per person
Dec 16 - Dec 23
found 17 hours ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
9.2/10 Wonderful! (1,677 reviews)

The Cheshire

The Cheshire

4 out of 5
Price was CA $2,103, price is now CA $1,692 per person
CA $1,692
per person
Dec 16 - Dec 23
found 17 hours ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
8.8/10 Excellent! (1,010 reviews)
A wonderful break from boring hotels! My kids loved all the artwork and the scavenger hunt. The pub food and drinks were fantastic, as was the hotel breakfast each morning. We will definitely plan to return.

Reviewed on Nov 9, 2026

Moonrise Hotel

Moonrise Hotel

4 out of 5
Delmar Loop
Price was CA $2,091, price is now CA $1,735 per person
CA $1,735
per person
Dec 16 - Dec 23
found 17 hours ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
9/10 Wonderful! (2,047 reviews)

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
Price was CA $2,151, price is now CA $1,809 per person
CA $1,809
per person
Dec 16 - Dec 23
found 17 hours ago
Roundtrip flight included
Toronto (YYZ) to St. Louis (STL)
8.6/10 Excellent! (1,080 reviews)
We were here for a wedding. Our room was very nice but my son’s bathroom was disgusting and not clean, they had to switch rooms and the only compensation they gave them was a food voucher. Not acceptable with blood and vomit not cleaned from previous guest. We expected more for this caliber of hotel.

Reviewed on Nov 8, 2026

Where to stay in Northeast Missouri

Find the best Northeast Missouri areas and neighborhoods for the activities you enjoy most. Learn more about Northeast Missouri
The illuminated Gateway Arch at night with a city skyline in the background.

Clayton

1 out of top 10 points of interest in this area

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Find hotels in Clayton

Ready to book your vacation to Northeast Missouri?

 

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Northeast Missouri Hotel Deals

Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
Fully refundableReserve now, pay when you stay
The price is CA $127 per night from Nov 15 to Nov 16
CA $127
CA $151 total
Nov 15 - Nov 16
includes taxes & fees
9.4/10 Exceptional! (3,367 reviews)
"Loved the comfortable bed. Isn't completely soundproof so you will hear the planes, but it is not bad. Temperature control was easy with the digital thermostat. The room was cleaned well. Would definitely stay there again next time I am in the area."

Reviewed on Nov 9, 2026

Pear Tree Inn St. Louis Airport
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $148 per night from Dec 6 to Dec 7
CA $148
CA $172 total
Dec 6 - Dec 7
includes taxes & fees
8.8/10 Excellent! (3,530 reviews)
"The staff were very kind and welcoming! We enjoyed our stay. The rooms were very clean and comfortable. It also has a lovely breakfast. My favorite part about my stay was definitely the entire staff though I can’t say enough how wonderful everyone was."

Reviewed on Nov 9, 2026

Clayton Plaza Hotel & Extended Stay
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
Fully refundableReserve now, pay when you stay
The price is CA $147 per night from Nov 15 to Nov 16
CA $147
CA $172 total
Nov 15 - Nov 16
includes taxes & fees
Pear Tree Inn St. Louis Near Union Station
See all 3,006 properties in Northeast Missouri
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Northeast Missouri attractions

The Saint Louis Zoo sign with vines on the wall.

St. Louis Zoo

9.2/10 (4,367 reviews)
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
See properties

What to do in Northeast Missouri

Be Bop and Beyond 18th and Vine Live Jazz and Walking Tour

Be Bop and Beyond 18th and Vine Live Jazz and Walking Tour

CA $49
per adult
Be Bop and Beyond 18th and Vine Live Jazz and Walking Tour
Kansas City Haunted Pub Crawl Ghostly Drinks and Stories

Kansas City Haunted Pub Crawl Ghostly Drinks and Stories

CA $49
per adult
Kansas City Haunted Pub Crawl Ghostly Drinks and Stories
Astounding Scavenger Hunt: Fountains, Fun & Hidden Finds

Astounding Scavenger Hunt: Fountains, Fun & Hidden Finds

CA $21
per adult
Astounding Scavenger Hunt: Fountains, Fun & Hidden Finds
See all activities in Northeast Missouri

Frequently asked questions

How much does a Northeast Missouri vacation package cost?
Live it up in Northeast Missouri from as little as CA $1,366. Choose from a great selection of flights, hotels and rental cars to suit your travel style. You can score even more discounts when you add a few sightseeing activities to your vacation package.
How do I get a cheap travel package to Northeast Missouri?
Our Northeast Missouri vacation packages promise plenty of savings for the savvy explorer. For the best deal, simply bundle your flights, hotels and extras (including tours) into a handy package. But low prices are only the start of your next memorable adventure. Book with Expedia and you'll have more than 550 airlines and 1,000,000 hotel options around the globe to choose from. No matter your budget or style, there's a vacation package that's perfect for you.
Where should I stay in Northeast Missouri?
You'll love St. Louis. Popular attractions, like Busch Stadium and Gateway Arch, will keep you entertained in this happening city.
What are the top hotels in Northeast Missouri?
For properties in St. Louis with comfy beds and friendly service, you can't top Hyatt Regency St. Louis at The Arch and Clayton Plaza Hotel & Extended Stay. If you're swinging by Wright City as well, you can look forward to a wonderful night's sleep at Holiday Inn Express Warrenton, an IHG Hotel or Super 7 Inn.
How far in advance should I book my Northeast Missouri vacation?
While not all airlines advertise ticket prices early, you can usually look up international flights on Expedia up to 12 months in advance. This is the time you'll bag some incredible deals. If you're booking late, you could still be in luck. Low prices sometimes become available a few weeks prior to departure.
What does an Expedia Northeast Missouri travel package include?
That depends on what you're looking for. If you're traveling solo, you might decide to combine hotels and flights. Bringing the whole crew to Northeast Missouri? A travel package including rental cars, flights and hotels might suit you better. Expedia gives you the flexibility to customize your travel package.
What should I know before booking a Northeast Missouri travel package?
Discover deals that fit your budget with an Expedia package. Airfares, hotels, rental cars — we're a one-stop shop for all of them. You'll save loads just for bundling your bookings. Whether you're embarking on a snow and ski adventure or kicking back on a warm beach, your dream getaway is only clicks away.
Can I choose my airline with a Northeast Missouri Expedia vacation package?
With a vacation package, the choice is in your hands. Whether you're hoping to fly to Northeast Missouri in business or coach, simply choose from the available airline options. Expedia has access to over 550 partner airlines globally.
If I'm not able to travel, can I cancel my Northeast Missouri vacation package?
If your vacation plans in Northeast Missouri have been upended, it's comforting to know that it's possible to amend or cancel your booking. If your booking was made within the last 24 hours, you may be able to get a refund. If your booking is older than that, your hotel, airline or car rental company may impose a fee. To find out more, check our Customer Service Portal.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.